Adult CF Clinical Trials
Upcoming & Enrolling Adult Cystic Fibrosis Clinical Trials
The studies listed below will soon be or are currently enrolling participants. Our list of upcoming studies is constantly evolving. Please contact our research team to learn about studies in our pipeline that may not be listed here!
To learn more about upcoming clinical trials in CF, visit the Cystic Fibrosis Foundation’s Clinical Trials Finder.
Last updated August 26, 2026.
“This study will look at pulmonary exacerbations, which are a worsening of respiratory symptoms, in people with CF who need to be treated with intravenous (IV) antibiotics. It will compare treatment with one antibiotic (a beta-lactam) to treatment with two antibiotics (tobramycin and a beta-lactam) to learn whether there is a difference in lung function and symptom improvement between the two groups.” – CFF Trial Finder Profile
Principal Investigator: Andrew Braun, MD, MHS
Lead Research Coordinator: Nikki Cole
Key Inclusion Criteria:
– 6 Years and Older
– Positive Pseudomonas aeruginosa culture in last two years
Time Commitment: 3 study visits over 48 days.
See CFF Trial Finder profile here.
See ClinicalTrials.gov profile here.
“The REACH observational study will collect health information on people with CF 12 years and older who do not take CFTR modulators.” – CFF Trial Finder Profile
Principal Investigator: Hara Levy, MD MMSc
Lead Research Coordinator: Nikki Cole
See CFF Trial Finder profile here.
See ClinicalTrials.gov profile here.
“This study will assess the safety and effectiveness of ANG003, a pancreatic enzyme replacement therapy (also known as “enzymes” or “enzyme therapy”) to see whether it works as well as the approved enzyme therapy Creon.” – CFF Trial Finder Profile
Key Inclusion Criteria:
– 18 years and older
– Diagnosed with Exocrine Pancreatic Insufficiency / prescribed Pancreatic Enzyme Replacement Therapy
Principal Investigator: Andrew Braun, MD, MHS
Lead Research Coordinator: Nikki Cole
See CFF Trial Finder profile here.
See ClinicalTrials.gov profile here.
Ongoing Adult Cystic Fibrosis Clinical Trials
The clinical trials listed below are currently ongoing and are no longer accepting new participants. Our studies are both investigational and observational. We enjoy working with families from all around the Midwest. Please contact our research team to learn about clinical trials in our pipeline that may not be listed here!
Last updated August 26, 2026.
“This study will test the effectiveness, safety, and tolerability of BI 1291583, a drug intended to reduce inflammation in the lungs.” – CFF Trial Finder Profile
Principal Investigator: Andrew Braun, MD, MHS
Lead Research Coordinator: Megan Devereaux
See CFF Trial Finder profile here.
See ClinicalTrials.gov profile here.